Ultra-Sensitive Mutation Detection CloDiA™ PCR Kits


Medaysis’ Ultra-Sensitive Mutation Detection Kits provide Clonal Differential Amplifier (CloDiA™) PCR using novel and proprietary primers to amplify somatic mutations and suppress or block the amplification of wild type gene in human genomic DNA.

CloDiA™ PCR includes two types of technique - Unindel™ PCR and Stuntmer™ PCR. Unindel™ PCR is designed to detect a broad range of insertions/deletions (universal insertions/deletions) in the target region. The three-primer set comprising forward primer, reverse primer and blocker inhibits amplification of wild type gene but enables amplification of exonic insertions/deletions.
Stuntmer™ PCR is designed to detect a broad range of point mutations in the target region. Dual port primer of R Port and E Port is designed for self-competition to preferably amply mutated gene but suppress wild type gene amplification.
 
This sensitive and specific method enables the detection of less than 1% (as little as 20 ng to 100 ng) of) mutant genes mixed with the wild type. Besides known mutations, this method can detect unknown mutations in the target region.


  • Detect known and unknown mutations in target Exons
  • Sensitive and specific amplification of mutant loci
  • Optimized protocol for reliable and reproducible results
  • Easy to use, straightforward analysis





























​​Products by Gene Types                                                                                                                                                 SDS


Cat. No.

Description
Size
Datasheet

ABL0001-20

ABL0001-50

Ultra-Sensitive ABL Mutation Detection Kit
20 tests
50 tests
ABL0001

AKT30001-20

AKT30001-50

Ultra-Sensitive AKT3 Mutation Detection Kit
20 tests
50 tests
AKT30001

ASXL10001-20

ASXL10001-50

Ultra-Sensitive ASXL1 Mutation Detection Kit
20 tests
50 tests
ASXL10001
ASXL10002-20
ASXL10002-50

Ultra-Sensitive cfDNA ASXL1 Mutation Detection Kit
20 tests
50 tests
ASXL10002

BRAF0001-20

BRAF0001-50

Ultra-Sensitive BRAF Mutation Detection Kit

20 tests

50 tests

BRAF0001

DNMT3A0001-20

DNMT3A0001-50

Ultra-Sensitive DNMT3A Mutation Detection Kit
20 tests
50 tests
DNMT3A0001
CALR0001-20
CALR0001-50

Ultra-Sensitive Calreticulin (CALR) Mutation Detection Kit
20 tests
50 tests
CALR0001

EGFR0001-20

EGFR0001-50

Ultra-Sensitive EGFR Mutation Detection Kit

20 tests
50 tests
EGFR0001
EGFR0002-20
EGFR0002-50

Ultra-Sensitive cfDNA EGFR Mutation Detection Kit
20 tests
50 tests
EGFR0002

FLT30001-20

FLT30001-50

Ultra-Sensitive FLT3 Mutation Detection Kit
20 tests
50 tests
FLT30001

HRAS0001-20

HRAS0001-50

Ultra-Sensitive HRAS Mutation Detection Kit
20 tests
50 tests
HRAS0001
IDH10001-20
IDH10001-50

Ultra-Sensitive IDH1 Mutation Detection Kit
20 tests
50 tests
IDH10001

JAK20001-20

JAK20001-50

Ultra-Sensitive JAK2 Mutation Detection Kit
20 tests
50 tests
JAK20001

KIT0001-20

KIT0001-50

Ultra-Sensitive KIT Mutation Detection Kit
20 tests
50 tests
KIT0001

KRAS0001-20

KRAS0001-50

Ultra-Sensitive KRAS Mutation Detection Kit
20 tests
50 tests
KRAS0001

NRAS0001-20

NRAS0001-50

Ultra-Sensitive NRAS mutation Detection Kit
20 tests
50 tests
NRAS0001

PI3KCA0001-20

PI3KCA0001-50

Ultra-Sensitive PI3KCA Mutation Detection Kit
20 tests
50 tests
PI3KCA0001

PTEN0001-20

PTEN0001-50

Ultra-Sensitive PTEN Mutation Detection Kit
20 tests
50 tests
PTEN0001

SF3B10001-20

SF3B10001-50

Ultra-Sensitive SF3B1 Mutation Detection Kit
20 tests
50 tests
SF3B10001

TET20001-20

TET20001-50

Ultra-Sensitive TET2 Mutation Detection Kit
20 tests
50 tests
TET20001

TP530001-20

TP530001-20

Ultra-Sensitive TP53 Mutation Detection Kit
20 tests
50 tests
TP530001


Products by Cancer Types                                                                                                                                                           


Breast                    EGFR    PIK3CA    TP53
ColorectalBRAF    EGFR    HRAS    KRAS    NRAS    PIK3CA    TP3
GastricPIK3CA    TP53
LeukemiaABL    ASXL1    CALR    DNMT3A    FLT3    IDH1   JAK2    KIT    KRAS    NRAS    PIK3CA    SF3B1    TET2    TP53
LiverBRAF    KRAS    PIK3CA    TP53
LungBRAF    EGFR    KIT    KRAS    PIK3CA    TP53
OvaryBRAF    EGFR    KIT    KRAS    NRAS    PIK3CA    TP53
ProstatePIK3CA    TP53




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